Molecular Characterization of Borrelia burgdorferi from Case of Autochthonous Lyme Arthritis
نویسندگان
چکیده
Miguel Delibes-Mateos, Catarina Ferreira, Francisco Carro, Marco A. Escudero, and Christian Gortázar Author affiliations: Instituto de Investigación en Recursos Cinegéticos, a collaborative agency of the Consejo Superior de Investigaciones Científicas, Universidad de Castilla-La Mancha, and Junta de Comunidades de Castilla-La Mancha, Ciudad Real, Spain (M. Delibes-Mateos, C. Gortázar); Trent University, Peterborough, Ontario, Canada (C. Ferreira); Estación Biológica de Doñana, Seville, Spain (F. Carro); and Ebronatura, Zaragoza, Spain (M.A. Escudero)
منابع مشابه
Direct molecular typing of Borrelia burgdorferi sensu lato species in synovial samples from patients with lyme arthritis.
Since Lyme arthritis was first described in the United States, it has now been reported in many countries of Europe. However, very few strains of the causative bacterium, Borrelia burgdorferi, have been isolated from synovial samples. For this reason, different molecular direct typing methods were developed recently to assess which species could be involved in Lyme arthritis in Europe. We devel...
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A murine IgM monoclonal antibody (MA-2C6) with κ-light chains directed against an antigenic determinant of outer surface protein A (OspA) of the Lyme disease spirochete, Borreliaburgdorferi, is produced. This antibody could bind specifically to OspA antigen of several isolates of B. burgdorferi, but not to the non-Lyme disease bacteria such as T. pallidum and B. hermsii. Antibody MA-2C6 was pur...
متن کاملReport of a case of Lyme disease in Mazandaran
Lyme disease is caused by the spirochete Borrelia burgdorferi. Depending on the stage of illness, infection may be limited to the skin or involve the cardiac, nervous and musculoskeletal systems. Herein, we report a case of Lyme disease in a 23-year-old woman from North of Iran (Mazandaran) in early-localized stage of erythema chronicum migrans. The diagnosis was confirmed by the presence of se...
متن کاملCharacterization of Borrelia burgdorferi proteins reactive with antibodies in synovial fluid of a patient with Lyme arthritis.
Four Borrelia burgdorferi proteins reactive with antibodies in the synovial fluid of a patient with Lyme arthritis were characterized. Homology between amino acid sequences of immunoreactive spirochetal proteins and human proteins, including members of the Escherichia coli GroEL protein family, suggests that antigenic mimicry may play a role in the pathogenesis of Lyme arthritis.
متن کاملTHE FIRST ENDEMIC CASE OF LYME BORRELIOSIS IN IRAN
This case report shows the existence of Lyme borreliosis disease in Iran and proves the existence of the spirochete Borrelia burgdorferi in Iran which had not been found before in the ticks of this region. It is important for our physicians to consider Lyme borreliosis in their differential diagnosis. Apart from skin manifestations, neurological, cardiac, articular and ocular lesions are no...
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عنوان ژورنال:
دوره 20 شماره
صفحات -
تاریخ انتشار 2014